Destroy All Humans! 2

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Destroy All Humans! 2

Game general and emulation properties:
ESRB rating: T (Crude Humor, Sexual Themes, Strong Language, Violence)
PEGI rating: 16+
OFLC rating: M
Widescreen supported natively
Progressive scan supported
Supports up to two local players
Languages supported:
English: SLES-54384 & SLUS-21439 & SLUS-29196 & SLUS-21439GH & SLED-54401
German: SLES-54384
French: SLES-54384
Spanish: SLES-54384
Italian: SLES-54384
Region NTSC-U:
Serial numbers: SLUS-21439
SLUS-21439GH (Greatest Hits)
SLUS-29196 (Demo)
Release date: October 17, 2006
October 17, 2007 (Greatest Hits)
CRCs: 42DF8C8C
Windows Status: Playable
Linux Status: ?
Mac Status: ?
Region PAL:
Serial numbers: SLES-54384
SLED-54401 (Demo)
Release date: October 20, 2006
October 26, 2006 (Australia)
Windows Status: Playable
Linux Status: Playable
Mac Status: ?

Developer(s): Pandemic Studios
Publisher(s): THQ
Genre: Action, Adventure
Wikipedia: Link
Game review links: Metacritic74/100
Game description: Destroy All Humans! 2 takes the irreverent Sci-Fi action gaming experience into the swinging sixties with all new game features, expanded open-world gameplay and co-op multiplayer. Assuming the role of the Furon Scout - Crypto 137 - players will embark on another mission to earth to take on the world of free love, the Cold War and other 60's era icons. In Destroy All Humans! 2 Players have access to an upgraded arsenal of weapons and enhanced mental abilities while they battle a variety of new enemies from secret agents and giant creatures to Soviet Forces and ninja warriors.
The sequel to Destroy All Humans!. The game is set in 1969, 12 years after the original. The game begins with a KGB slide show meeting showing that the main character from Destroy All Humans!, Cryptosporidium-137, is now deceased for unknown reasons. His clone, Cryptosporidium-138 (Crypto for short), made of more pure Furon DNA, is now taking his place and continuing to pose as the United States President. KGB intelligence reveals that Crypto-138 is the first and only Furon to have genitalia, referred to only as "The Package". Seeing the Furons as a threat to the Soviet Union, the KGB destroy the Furon mothership with a nuclear missile. Soon after, Crypto's new adventure begins.

Test configurations on Windows:

Environment Configurations Comments Tester
Region OS CPU/GPU Revision Graphics Sound/Pad
  • Intel Core i7 2600
  • Nvidia GTX 550 Ti
r4600 0.9.8 ? ? FPS: 55-60 FPS, None, major slowdown on all, Native Resolution, In-game a sort of "shadow" is on the screen, but blocky showing vague things of the environment, but past that is the game, which would look normal if not for that, and scaling also major slows it down and ANY hacks do, too. (So no hacks) All menus are fine. Could play through entire if one could get past the blocky shadow. Bot2345
  • Intel i5 2500K @3400Mhz
  • GeForce GTX 460 SE 768MB
v1.1.0 r5423 GSdx r5412
  • SPU2-X v2.0.0 r5421
  • LilyPad v0.11.0 r5403
BIOS: Any, HACKS: Skipdraw 5 in GSdx is recommended, when playing in hardware mode., Full screen shadow like issue in the whole game., Runs fine in hardware mode at 3x upscale. Skipdraw 5 needed in this mode. Check known issues. Software mode has no graphical issues. The game is fully playable. Be aware that sw mode is highly demanding. With above PC specs it uses around 70% CPU power! Can get slowdowns in intense fightings. Yuri
NTSC-U Windows
  • Intel Core i7 @ 3.4Ghz
  • Nvidia GTX 285 768MB
1.1.0 r5604 GSdx 5580 SSE41
  • SPU2-X 2.0.0
  • LilyPad 0.11.0
Ingame has corrupt graphics if gsdx is in hardware mode. Looks fine in software mode.
NTSC-U Windows
  • AMD Athlon II X2 4450e 3.51GHZ
  • ATI HD Radeon 5450 1GB DDR3
1.1.0 Development 5704 GSDX
  • SPU2-X
  • ?
Europe v02.20(10/02/2006), INTC Rotation Detection, Haven't found any issues. Playing great with around 30-38 FPS in Full Screen.
NTSC-U Windows 7 64-Bit
  • Intel i7 @ 3.4Ghz
  • Sapphire R9 290X 4GB
1.2.1 r5875 GSdx 10 (Hardware) 0.1.16 r5875
  • SPU2-X r5875
  • Lillypad 0.11.0 r5875
The same thing as Yuri said. Skipdraw and 3X native did not seem to get rid of the graphical glitch, but your mileage may vary.Bios v 2.0 was used. Zrooney
PAL Windows 7
  • Intel i5 4670K @4.2Ghz
  • GeForce GTX 770 4GB
v1.5.0 (git 2534) GSdx DX11 Hardware
  • SPU2-X v2.0.0 r5421
  • LilyPad v0.12.1
Solid 60 FPS, Skipdraw 5X Scaling 4X. Some issues where the subtitles and the dialog options are not displayed, no character shadows. Strange texture glitches are now fixed. Arkelyos
PAL Windows 10
  • AMD FX8320 Black 8Core @4GHz
  • Saphire r390 8GB Nitro
v1.6.0 GSdx 1.2.0 - SSE4
  • SPU2-X v2.0.0 r5421
  • LilyPad v0.12.1
BIOS: Japan V01.00. Fair Performance mostly 90+% but does drop to 80% every now and then - I will still enjoy completing the game , Skipdraw hack to fix HW Rendering sadly removes shadows but thats better than having to run it native res and my cpu cant run software very fast. Some bugs with HUD but nothing major. My Rig does not run DX11 HW properly; the ground and a lot of environmental objects do not render so i had to switch to OpenGL. Xproflipscarab

Test configurations on Linux:

Environment Configurations Comments Tester
Region OS CPU/GPU Revision Graphics Sound/Pad
PAL Solus, kernel 5.0.16
  • Intel Core i5-4570 CPU @ 3.20GHz
  • NVIDIA GeForce GTX 650 2 GB
1.5.0 (075a9f3) GSdx 1.1.0 AVX2
  • SPU2-X 2.0.0
  • OnePAD 0 1.3.0
Works full speed on software mode. Finished the game with no serious issues. Hardware mode has some effect issues. Ratchet66


  • The game has a built-in 16:9 widescreen mode. To enable it start the game and go to Options > Display > Widescreen menu.

Known Issues

Shadow-like glitch

  • Status: Active
  • Type: Minor
  • Description: In-game a sort of "shadow" is on the screen, but blocky showing vague things of the environment. The glitch is present entire game.
  • Workaround: Switch to Software mode by going to Config > Video (GS) > Plugin Settings, and setting Renderer to any of the "(Software)" options.
  • Alternative Workaround: Go to Config > Video (GS) > Plugin Settings, click "Enable HW Hacks", go to Configure Hacks and set "Skipdraw" to 5. This causes character shadows (and some post processing effects) to disappear and triggers a texture popping issue on far away objects.

Software mode objects falling

  • Status: Active
  • Type: Serious
  • Description: In Software mode during intense fighting scenes, objects tend to fall through the level(eg. grabbing vehicles with the saucer, NPCs getting stuck in the ground). The player character can have this issue too, but very rarely. The issue might be connected to high CPU usage.
  • Workaround: Go to Config > Video (GS) > Plugin Settings, and set Renderer to any of the "(Hardware)" options. Or press the F9 key to temporarily switch to Hardware mode. Or just avoid too many enemies closing in at the same time.

Geometry fails to render while using DX11 Hardware

  • Status: Active
  • Type: Serious
  • Description: When using DX11 HW mode the ground and other geometry do not render AKA Completely invisible (PCSX2 revision 1.6.0).
  • Workaround: OpenGL HW works very well so I'd say if you have this problem switch to OpenGL

The gallery

Public compatibility forum links